FINAL ASSIGNMENT

- due at beginning of final exam: December 12, 2006



1.  Assume that all conditions are met for genetic equilibrium.  Demonstrate the phenomenon of Hardy-Weinberg equilibrium for the following populations.  Begin with a population which in the first generation has no heterozygotes.  Continue until you are satisfied that you have demonstrated the concept and effect of H-W equilibrium:
    a.  f(A) = 0.5
    b.  f(A) = 0.8
    c.  f(A) = 0.3

2.  A population has been in equilibrium for many generations, when suddenly a change in the environment causes certain genotypes or phenotypes to be less adaptive.  Assume that all other conditions for genetic equilibrium continue to be met, but selection occurs as follows.  For each of the following populations and selection criteria, follow the population genotypes and phenotypes for five (5) generations after the initial one (given).
    a.  f(A) = 0.5    A change in the environment causes 50% of recessive phenotype individuals to die.
    b.  f(A) = 0.5    A change in the environment causes heterozygotes to die.
    c.  f(A) = 0.5    A change in the environment causes 50% of dominant phenotype individuals to die.
    d.  f(A) = 0.9    A change in the environment causes heterozygotes to die.
    e.  f(A) = 0.9    A change in the environment causes homozygous recessives to reproduce at twice the normal rate (twice the rate of anyone else).

3.  Show what happens to a small isolated population of 10 individuals (5 mating pairs) for five (5) generations after the initial one (given).  Keep the population the same, that is, 10 individuals (5 mating pairs), in each generation.  Assume that all other equilibrium conditions are met.
    a.  f(A) = 100%        A mutation introduces one recessive individual into the population.
    b.  f(a) = 100%        A mutation introduces one homozygous dominant individual into the population.
    b.  f(a) = 100%        A mutation introduces one dominant phenotype, heterozygous individual into the population.